莫妮卡·克莱曼（Monica Kleinman）

莫妮卡·克莱曼（Monica Kleinman）博士对小儿复苏有强烈的临床和学术兴趣，包括制定基于证据的治疗指南。克莱曼（Kleinman）博士一直担任美国心脏协会（AHA）的志愿者已有30多年了。In 2003 she was appointed to the AHA’s National Emergency Cardiovascular Care Committee's Pediatric Subcommittee and subsequently served as its chair from 2007 through 2009. Dr. Kleinman's contributions include serving as an editor of the 2006 version of the Provider and Instructor Textbooks for Pediatric Advanced Life Support (PALS), and writing group chair for the 2010 AHA PALS Guidelines and 2015 AHA Basic Life Support Guidelines. From 2011 through 2015 she served as co-chair of the Pediatric Task Force for the International Liaison Committee on Resuscitation (ILCOR), the international consortium that develops consensus statements on resuscitation science and treatment recommendations. Currently Dr. Kleinman serves as a Domain Lead for the ILCOR continuous evidence evaluation process.

Kleinman博士也热爱病人安全ty and harm prevention, including the early identification of patient deterioration outside of the critical care setting. She developed the early warning score system used at Boston Children’s Hospital and has published several reports on its use as a predictor of deterioration in specific patient populations as well as in resource-limited settings. She is also interested in in-hospital emergency response systems in Children’s Hospitals, the use of checklists for improving patient safety, and inter-facility transport for critically ill children.

Kleinman博士曾担任过多项患有罕见疾病后代儿童的临床试验的首席研究员。受影响的儿童似乎会过早年龄，生长不良，脱发，皮肤紧绷和关节染色，最重要的是，动脉粥样硬化加速。儿童在平均年龄为14岁的心血管事件（心脏病发作，心力衰竭和中风）死亡。后代的遗传原因是层粘连蛋白A基因中的单个碱基对突变，从而导致突变层粘连蛋白A蛋白的产生。该蛋白质被称为过程，永久插入到核膜中，导致组织和器官功能障碍。临床试验旨在减少孕激素的产生，并加速其从受影响细胞中消除。波士顿儿童医院进行的三项介入试验表明，一种药物lonafarn欧宝彩票平台ib可改善血管扩张，并延长该疾病儿童的寿命。