传染病研究|Overview
Research in the Division of Infectious Diseases includes both basic investigation and clinical research. The bench research in the division has the broad objective of elucidating basic mechanisms of microbial pathogenesis and the related host responses that mediate susceptibility to infection, host injury, and protective immunity. Investigation targets viral, bacterial, fungal, and parasitic pathogens of major significance in community acquired infections in the United States, in infections of immunocompromised hosts, and in global public health. Current projects include:
- pathogen-host signaling in streptococcal infection
- novel strategies for pneumococcal vaccines
- enhancing innate and adaptive immunity in neonates
- regulation of bacterial virulence gene expression
- modeling cholera infection and host responses in Drosophila
- HIV pathogenesis, immune response, and vaccine development
- regulation of morphogenesis in Candida albicans
- molecular approaches to malaria pathogenesis
Clinical research is focused in two broad areas: clinical trials in pediatric HIV and clinical epidemiology/clinical decision-making.
Researchers in the Division of Infectious Diseases hold faculty appointments at Harvard Medical School.
Latest Research in Infectious Diseases:
RESEARCHER | FOCUS AREA |
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Anna Aldovini, MD |
HIV biology |
Thea Brennan-Krohn, MD | |
Sandra Burchett, MD, MS |
病毒感染 |
Simon Dove, PhD |
Transcription regulation |
David Dowling, PhD | |
Jeffrey Dvorin, MD, PhD |
Malaria, Parasitology, Tropical Medicine |
Sylvia Fischer, PhD |
宿主对病毒感染和(复古)转座子活性的反应,小RNA介导的基因调节 |
Lakshmi Ganapathi, MBBS |
Clinical Research in Immunocompromised/Transplant Infectious diseases, HIV/Hepatitis C harm reduction in adolescents |
Courtney Gidengil, MD, MPH |
Pediatric Health Services Research |
Donald Goldmann, MD |
Bacterial Infection |
Robert N. Husson, MD |
Molecular pathogenesis of mycobacterial infection |
Dennis Kim, MD, PhD | 宿主菌相互作用,先天免疫的遗传学 |
Julia R. Koehler, MD |
菌;白色念珠菌 |
Ofer Levy, MD, PhD |
Innate immunity of the human newborn |
Yingjie Lu,博士 |
vaccine development for infectious disease |
Richard Malley, MD |
肺炎球菌发病机理和免疫力,疫苗发育 |
Kristin Moffitt, MD |
Host bacterial pathogen interactions, Bacterial vaccine development |
Mari Nakamura, MD, MPH |
Vaccine health services research, Health information technology |
Gregory Priebe, MD
Gregory Priebe, MD Gregory Priebe, MD |
Pseudomonas aeruginosa infections |
Seth Rakoff-Nahoum, MD, PhD | Mechanistic Evolutionary Ecology of Host-associated Microbiomes |
Thomas J. Sandora, MD, MPH |
|
Hospital epidemiology, Hand hygiene, Healthcare-Associated Infections, Infection Prevention & Hospital Epidemiology |
|
Tanvi Sharma, MD, MPH |
Pediatric HIV, Immunocompromised infectious diseases |
Simon van Haren, PhD | Molecular mechanism of vaccine adjuvants, Vaccine Development |
Ana M. Vaughan, MD, MPH |
Hospital epidemiology, Infection Prevention and Control, Healthcare-associated infections, Immunocompromised infectious diseases |
Paula I. Watnick, MD, PhD |
Impact of diarrheal pathogens on host metabolism and development; Vaccines and therapeutics for bacterial infection |
Michael R. Wessels, MD |
Streptococcus infection |
Fan Zhang, PhD |
Vaccine Development; Immune Mechanism of Protection Against Human Pathogens |