Basic Research |Overview
TheRao Laboratoryseeks to understand how the intrinsic nerve circuits of the gastrointestinal tract normally regulate digestive health, and how dysfunction in these circuits leads to digestive disease.
TheHansen Laboratorystudies the role of Ras-like GTP-binding proteins in epithelial morphogenesis and oncogenic transformation.
TheKagan Laboratoryis focused on understanding the regulation of innate immunity at the level of microbial detection and signal transduction. Of particular interest is the family of Toll-like receptors (TLRs), which evolved to specifically link microbial detection to the control of adaptive immunity.
TheLencer Laboratoryand four NIH-funded core laboratories form a consortium of scientists focused on gastrointestinal research.
TheSnapper Laboratoryis part of a larger consortium of talented interdisciplinary investigators that focuses on gastrointestinal research.
TheZanoni Laboratoryseeks to understand the events that initiate protective immunity in response to infection and tissue injury, or that drive the development of immune-mediated diseases
TheChinnapen Laboratoryfocuses on both the development of novel technologies to deliver biologic drugs across cellular membrane barriers, and to better understand the cellular mechanisms that underpin this transcellular transport.