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阅读障碍和阅读障碍|Overview

BOLD: Boston Longitudinal Study of Dyslexia

PI:Nadine Gaab, PhD

Participants: Pre-readers ages 4-6, with and without a family history of developmental dyslexia

Developmental dyslexia is a common learning disability, which affects 5-17% of children. In this study, we aim to use both behavioral and neuroimaging measures to shed light on brain development in pre-reading children, both with and without a family history of dyslexia. By identifying differences between these two groups, we aim to allow for the early prediction of dyslexia. This would translate to more effective interventions before a child ever enters school and begins learning to read, resulting in the easing of the clinical, psychological, and social difficulties that are often assocated with dyslexia. We will follow our participants for four years as they go through the process of becoming readers.

For full participation details, clickhere, or contact the Gaab Lab viae-mailor at 857-218-3022.

Detecting Early Signs of Dyslexia in Infancy

PI:Nadine Gaab, PhD

Participants: typically-developing infants between 3 to 15 months of age.

发展性阅读障碍是一种学习障碍,其特征是难以准确或流利的阅读和拼写差。研究人员表明,被诊断出患有阅读障碍的儿童和成人的大脑与同一年龄的其他人的组织方式不同,并且还提供了证据表明对家庭阅读障碍的敏感性可能在家庭中受到影响。在我们的研究中,我们的目标是找到早期的阅读障碍迹象,以便尽快确定苦苦挣扎的读者,并尽早为他们提供正确的支持系统。众所周知,阅读障碍会在家庭中运行,这意味着,如果一个家庭成员患有阅读障碍或阅读困难,那么孩子患阅读障碍的风险更高。在观察大脑时,我们已经看到与没有人的家庭病史的儿童在开始学习阅读之前的差异。我们正在尝试确定这些大脑差异的出现如何,它们会随着时间的流逝如何发展,以及他们是否可以用来识别在学龄前甚至婴儿期处于阅读障碍风险的孩子。

In this study we will compare the brain images of infants with and without a family history of developmental dyslexia using Magnetic Resonance Imaging (MRI). MRI is a safe and non-invasive imaging method many researchers and clinicians use to take pictures of the brain. We will utilize age-specific behavioral techniques and innovative MRI technology in order to safely acquire these brain images without using any sedation or anesthesia. To accomplish this, we take pictures of the brain while babies are naturally sleeping in our nursery at Children’s Hospital Waltham. During your visit, we try to re-create your baby’s typical napping routine at home in our nursery. We work to personalize every try based on the parent-infant napping routine, whether that means allowing mom to nurse and rock her baby to sleep, placing the baby in an MRI-safe crib to fall asleep independently, or playing with the baby until he/she gets sleepy. If we are successful taking pictures of the baby brain families can take home a CD with their baby’s brain picture.

For full participation details, clickhere, or contact the Gaab Lab viae-mailor at 857-218-3022.

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