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What is a lymphatic malformation?

A lymphatic malformation is a sponge-like collection of abnormal growths that contain clear fluid. It is probably caused by a developmental error in the womb, and no known food, medication or activity during pregnancy can cause a lymphatic malformation.

Lymphatic malformations can be related to certain conditions, including:

  • Gorham-Stout: A type of lymphatic malformation that occurs in bones and partially destroys them.
  • Milroy disease: An inheritedlymphedema(generalized swelling typically occurring in the legs) that is present at birth.
  • Lymphangioma circumscriptum: An abnormal collection of tiny lymphatic cysts.
  • Angiokeratoma:一群引起的皮肤损伤,黑暗的再保险d to black in color, and about 1 to 10 mm in size. Because these lesions often bleed spontaneously or following abrasion, treatment may be required to control bleeding.

What are the symptoms of a lymphatic malformation?

Lymphatic malformations typically lie just beneath the skin in the neck and the armpit, although they can also occur in other organs and in bones. They appear as a swelling and sometimes more extensive enlargement of soft tissues and bones.

A lymphatic malformation in the skin looks like tiny clear bubbles that often become dark red due to bleeding. Lymphatic malformations can cause the enlargement of any part of the body, including the lip, cheek, ear, tongue, limb, finger or toe.

The two major complications are infection and bleeding. A long-term complication of a lymphatic malformation is the overgrowth of involved tissues and bones.

How we care for lymphatic malformations

The clinicians at theVascular Anomalies Centerat Boston Children's Hospital care for andtreatchildren with lymphatic malformations. Theteamconducts research that may lead to the development of new, more effective therapies and result in ways to prevent these anomalies.

Lymphatic Malformation |Diagnosis & Treatments

How are lymphatic malformations diagnosed?

Before birth, lymphatic malformations can often be detected by anultrasound. Usually, your child’s medical history and physical examination will be enough for your doctor to make the diagnosis.Magnetic resonance imaging(MRI) with contrast enhancement is used to confirm the diagnosis and determine the extent of the lymphatic abnormality.

What are the treatment options for lymphatic malformations?

Left untreated, lymphatic malformations can result in pain, bleeding and infection. If your child’s lymphatic malformation causes any of these complications, your physician will recommend treatment based on the depth, location and severity of the malformation.

Treatment options include:

  • sclerotherapyto shrink the malformation
  • immunosuppressant medicationto reduce pain and slow the growth of abnormal lymphatic vessels
  • surgerymay be helpful to remove small, localized malformations completely without affecting surrounding structures

Lymphatic Malformation |Programs & Services

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