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What is a choroid plexus brain tumor?

脉络丛脑肿瘤在位于大脑空间的组织中形成,称为心室。这种组织使脑脊液(CSF)围绕着大脑和脊髓。这些罕见的肿瘤在年幼的孩子中更常见。在生命第一年内发生的10%至20%的脑肿瘤是脉络丛肿瘤。

How are choroid plexus tumors classified?

成功治疗孩子的脑肿瘤取决于您的孩子患有哪种类型的脉络丛肿瘤。Dana-Farber/Boston儿童的医生将使您的孩子的肿瘤归类为以下类型:

  • Choroid plexus papillomas (CPPs): These are one of two types of choroid plexus tumor that grow slowly, rarely spread and are by far more common.
  • Atypical plexus papillomas (APPs): Like CPPs, these tumors grow more slowly than their aggressive counterparts and rarely spread.
  • Choroid plexus carcinomas (CPCs)grow more aggressively and are more likely to spread than either APPs or CPPs. CPCs are less common, accounting for 25-35 percent of all choroid plexus tumors.

Choroid plexus papillomas are often easier to treat than carcinomas. An APP can act more aggressive but usually behaves like a CPP.

How we care for choroid plexus brain tumors

Children with choroid plexus tumors are treated through the脑肿瘤中心c atDana-Farber/Boston Children's Cancer and Blood Disorders Center,一个世界知名的目的地,针对患有恶性和非恶性大脑和脊髓肿瘤的儿童。我们的脑肿瘤专家在治疗包括脉络丛肿瘤在内的所有类型的神经肿瘤方面具有广泛的专业知识。

脉络丛脑肿瘤|症状和原因

脉络丛肿瘤的症状是什么?

of Brain tumors can cause a variety of symptoms in children depending on their size and location. Keep in mind that the symptoms of a brain tumor may resemble other more common conditions or medical problems. It is important to consult your child's physician for a diagnosis.

Choroid plexus tumors symptoms are most often associated with increased pressure in the brain and can include:

  • 头痛,通常在早上醒来时
  • irritability, particularly in younger children who can’t express where they have pain
  • 头大小增加(在婴儿中看到)
  • hydrocephalus – blockage of the normal flow of cerebrospinal fluid; pressure can increase in the brain and the skull can enlarge
  • 恶心和呕吐。这些症状通常在早晨更糟,整天有所改善
  • 昏睡
  • problems feeding or walking
  • 扩大的fontanelles,是婴儿头骨骨头之间的“软斑”

What causes choroid plexus tumors?

As a parent, you undoubtedly want to know what may have caused your child’s tumor. It’s important to understand that these and other brain tumors most often occur with no known cause. There’s nothing that you could have done or avoided doing that would have prevented the tumor from developing.

One rare genetic disease called Li-Fraumeni syndrome can be associated with choroid plexus tumors. If your child has a choroid plexus tumor their doctors will talk to you about genetic testing for Li-Fraumeni syndrome.

脉络丛脑肿瘤|诊断和治疗

脉络丛肿瘤如何诊断?

The first step in treating your child is forming an accurate and complete diagnosis. Choroid plexus tumors are most commonly diagnosed from imaging studies and biopsy.

Choroid plexus tumor diagnostic tests may include:

您的医生可能会根据孩子的个人情况与您讨论其他诊断测试。在完成所有必要的测试之后,我们的专家开会以审查并讨论他们对您孩子状况的了解。然后,我们将与您和您的家人会面,讨论结果并概述最佳的治疗选择。

What are the treatments for choroid plexus tumors?

您的孩子的医生将根据几个因素来确定特定的治疗方法,包括孩子的年龄,病史,肿瘤的类型,位置和大小以及疾病程度。

Choroid plexus tumor treatment may include:

What is the long-term outlook for choroid plexus tumors?

Patients with choroid plexus papilloma do extremely well with surgery. Children with choroid plexus carcinoma have a more guarded prognosis and often require aggressive treatment.

The five-year survival rate for children with CPP is 80 to 100 percent following complete surgical removal of the tumor and about 70 percent with partial removal. CPC requires additional postoperative treatment, with a survival rate of about 60-65 percent.

对于进行性或复发性脉络丛肿瘤的儿童有许多标准和实验治疗选择。复发性肿瘤可能需要第二次手术,然后进行化学疗法或放射治疗。

脉络丛脑肿瘤|Programs & Services

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